The film is based on four stories by Conan Doyle - "The Adventure of the Engineer's Thumb", "The Adventure of the Second Stain", "The Adventure of the Bruce-Partington Plans", "His Last Bow".
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The plot is an original story not based on any of Sir Arthur Conan Doyle's Holmes tales, though it bears some similarity to "The Bruce-Partington Plans." Oscar Homolka was originally cast as Holmes's elder brother Mycroft, but for family reasons he refused and Mycroft's character was replaced by "Mr. Ahrens" played by Holmes Herbert.