It contained a drug, as Holmes expected, but there was also a letter there from a man named Lowenstein who, it turns out, is a quack whose help the professor sought out as a way of achieving rejuvenation, which he thought would be advisable if he were going to marry a young woman.
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It was only through a letter from a friend sent to Mr. Bennett that the family learnt that Professor Presbury had been to Prague.
A fictional character in The Adventure of the Creeping Man, a Sherlock Holmes story by Sir Arthur Conan Doyle
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