Scanlan's is best-remembered for featuring several articles by Hunter S. Thompson, and especially for what is considered the first instance of gonzo journalism, Thompson's "The Kentucky Derby Is Decadent and Depraved".
It was later reprinted in Tom Wolfe's anthology The New Journalism (1973) and also in one of Thompson's own books The Great Shark Hunt (1979), a book collecting several of his earlier works.
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In 1970, Bill Cardoso (editor of The Boston Globe Sunday Magazine), wrote Thompson praising the "Kentucky Derby" piece in Scanlan's Monthly as a breakthrough: "This is it, this is pure Gonzo. If this is a start, keep rolling."
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