Karen served as the head writer for The Rosie Show which aired on the Oprah Winfrey Network.
On the other hand, The Hollywood Reporter said the show was “ramshackle” and “a little crazy” but called it interesting to watch.
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In September 2011, Selan joined the house band as a keyboardist, vocalist and trumpet player for Rosie O'Donnell's "The Rosie Show" which aired on Oprah Winfrey's OWN network.