Theobroma species are used as food plants by the larvae of some moths of the genus Endoclita, including E. chalybeatus, E. damor, E. hosei and E. sericeus.
Tropical house - Collections include Ananas comosus, Annona muricata, bromeliads, Caryota mitis, Cocos nucifera, Coffea arabica, cycads (including a Dioon spinulosum given by Smith College in the 1920s), Heliconia vellerigera, Kigelia pinnata, Musa, orchids, Oryza sativa, Piper nigrum, Rhizophora mangle, and Theobroma cacao.
Moniliophthora roreri, a pathogen of cocoa and other species in or related to the genus Theobroma