GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins.
Harold Dadford West (July 16, 1904 – March 5, 1974) was an American biochemist who was the first to synthesize threonine.
Phosphorylation of serine and threonine residues is conserved during MHC class I and MHC class II antigen processing.
Examples and other names in common use include Cdc5, Cdc5p, Plk, PLK, Plk1, Plo1, POLO kinase, polo serine-threonine kinase, polo-like kinase, polo-like kinase 1, serine/threonine-specific Drosophila kinase polo, and STK21.
Common ingredients in relaxation drinks may contain kava root, melatonin, valerian root, gamma-aminobutyric acid (GABA), Chamomile, Melissa officinalis, L-Theanine, L-Threonine, 5-Hydroxytryptophan or Passiflora.
These proteins interact with a conserved family of cell surface serine/threonine-specific protein kinase receptors, and generate intracellular signals using a conserved family of proteins called SMADs.