Trichothecenes are a very large family of chemically related mycotoxins produced by various species of Fusarium, Myrothecium, Trichoderma, Trichothecium, Cephalosporium, Verticimonosporium, and Stachybotrys.
Joffe's professional interests were centered primarily in toxigenic fungi associated with production of mycotoxins (aflatoxins, trichothecenes, and other toxins); ecology and environmental factors favoring formation and distribution of Fusarium mycotoxins in cereal grains, feeds and foods; and phytotoxic action of Fusarium strains, and their toxicity in animals and humans.