Tsalenjikha is the birthplace of the famous Georgian poet, Terenti Graneli.
At various periods of its existence, the Catholicate of Abkhazia was subdivided into several dioceses (eparchies), including those of Bichvinta, Kutaisi, Gelati, Tsageri, Tsaishi, Tsalenjikha, Chkondidi, Khoni, Ninotsminda, Nikortsminda, Shemokmedi, Jumati, Dranda, Bedia and Mokvi, centered on the respective cathedrals.
Built in the 12th-14th centuries, the Tsalenjikha Cathedral is a central cross-domed church with a narthex and three arcaded galleries two of which, that to the south and north, had been converted into the familial chapel of the House of Dadiani.