As such, it was the title of a famous short story, "Big Two-Hearted River", by U.S. author Ernest Hemingway.
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The story, set after World War I, was first published in 1925 as part of the collection In Our Time and republished in 1972 as part of The Nick Adams Stories.
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Bell's Brewery, a craft brewery based in Kalamazoo, Michigan, makes a highly rated (second best beer in the United States according to Zymurgy Magazine, the publication of the American Homebrewers Association) India Pale Ale named Two Hearted, with a graphic that features the river.
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