This event marked the first time that an Ultimate Fighter contestant, season one's Nate Quarry, would compete for a UFC championship.
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Headlining the card were the two coaches from The Ultimate Fighter 2, Rich Franklin and Matt Hughes, scheduled to defend their middleweight and welterweight titles, respectively.
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At UFC 56 on November 19, 2005, Franklin defended his title against Nate Quarry, a competitor from season 1 of The Ultimate Fighter.