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It is created as a byproduct of nandrolone via the 5-alpha reductase enzyme and is on the list of substances prohibited by the World Anti-Doping Agency since it is a detectable metabolite of nandrolone which is an anabolic steroid.
In 2009, the French Anti-Doping Agency, suspected that AICAR had been used in the 2009 Tour de France.
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Although a detection method was reportedly given to the World Anti-Doping Agency, it was unknown if this method was implemented.
Both players tested positive for methylhexaneamine, a "non-specified stimulant" on the prohibited substances list of WADA.
Luskin was lead counsel for Lance Armstrong after the June 2012 allegations of blood doping by the US Anti-Doping Agency, a quasi-official American sports governing entity.
The drug was made public when the United States Anti-Doping Agency was contacted by an anonymous athletics coach, later identified as Trevor Graham, who claimed that several top athletes were using THG as an illegal performance enhancing drug.
It also ensures all sports bodies in the UK comply with the World Anti-Doping Code as set out by the World Anti-Doping Agency (WADA).