A Spanish mission, Santa Isabel de Utinahica, was established in the chief town of the Utinahica on the Altamaha River, near the present site of Jacksonville, Georgia, in the first half of the 17th century.
Santa Isabel de Utinahica (ca. 1610-ca. 1640) was a 17th-century Spanish mission believed by the Fernbank Museum of Natural History to be located in modern-day Telfair County, Georgia, near Jacksonville.