Avenida Vicuña Mackenna (Vicuña Mackenna Avenue) is one of the main transport arteries of Santiago, Chile, joining Santiago center with more remote urban centers such as the communes of La Florida and Puente Alto.
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It crosses the communes of Santiago, Providencia, Ñuñoa, San Joaquín, Macul and La Florida and intersects with the urban highway Autopista Vespucio Sur.
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Vicuña Mackenna Avenue begins at the intersection between the Alameda, in Plaza Italia, extending south towards the commune of Puente Alto, where its name changes to Avenida Concha y Toro.
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