WLOX was the first television station on the Mississippi Gulf Coast, having begun operations September 15, 1962.
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The station's front website banner also incorporated a "CBS - coming soon" link to the advertisement on YouTube suggesting a future digital subchannel with a schedule from the network for the market would be offered through WLOX.
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The addition of CBS to WLOX-DT2 is be similar to a launch made by sister station WALB in Albany, Georgia.