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5 unusual facts about Wellcome Trust Sanger Institute


FASTQ format

It was originally developed at the Wellcome Trust Sanger Institute to bundle a FASTA sequence and its quality data, but has recently become the de facto standard for storing the output of high throughput sequencing instruments such as the Illumina Genome Analyzer.

Giocangga

In 2005, a study led by a researcher at the British Wellcome Trust Sanger Institute suggested that Giocangga might be the ancestor of over 1.5 million people, mostly in northeastern China and Mongolia.

Gordon Dougan

Professor Gordon Dougan is Head of Pathogen Research and a member of the Board of Management at the Wellcome Trust Sanger Institute (WTSI) in Cambridge, United Kingdom.

Maria Leptin

Successively, she had two more experiences abroad as a visiting Professor at École Normale Supérieure, Paris, France (2001) and as visiting scientist at Wellcome Trust Sanger Institute, Hinxton, UK (2004-2005).

Pileup format

Tony Cox and Zemin Ning at the Wellcome Trust Sanger Institute, but became widely known through its implementation within the SAMtools software suite.


Cancer genome sequencing

The Sanger Institute's Cancer Genome Project, first funded in 2005, focuses on DNA sequencing.

CUTL1

Researchers from the Wellcome Trust Sanger Institute reported that the mutation of CUX1 reduces the inhibitory effects of a biological inhibitor, PIK3IP1 (phosphoinositide-3-kinase interacting protein 1), resulted in higher activity of the growth promoting enzyme, phosphoinositide 3-kinase (PI3K) which leads to tumor progression.

Europhenome

The development of EuroPhenome is in collaboration with the Helmholtz Zentrum München, the Wellcome Trust Sanger Institute, and the Clinique de la Souris (France).

Genomic Standards Consortium

Established in September 2005, this international community includes representatives from a range of major sequencing and bioinformatics centres (including NCBI, EMBL, DDBJ, JCVI, JGI, EBI, Sanger, FIG) and research institutions.


see also

Cancer genome sequencing

The two main projects focused on complete cancer characterization in individuals, heavily involving sequencing include the Cancer Genome Project, based at the Wellcome Trust Sanger Institute and the Cancer Genome Atlas funded by the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI).