West Coast Shoe Company, maker of Wesco work boots, based in Scappoose, Oregon
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Wesco Financial, a diversified financial corporation based in Pasadena, California
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WESCO International, an electrical distribution company based in Pittsburgh, Pennsylvania
The sign was demolished when the Wesco Building was razed in the autumn of 1998 to make way for PNC Park, which succeeded Three Rivers as the home of the Pittsburgh Pirates.