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Born in Bas-Congo, Belgian Congo (now the Democratic Republic of the Congo), Helene Mambu received her Bachelor of Science degree in bio-chemistry in 1972 from Western College (now part of Miami University) in Oxford, Ohio, and went on to pursue and earn a medical degree in 1976, from Howard University in Washington, DC.
Following the work of Richard Nisbett, which showed that there were differences in a wide range of cognitive tasks between Westerners and East Asians, Jonathan Weinberg, Shaun Nichols and Stephen Stich (2001) compared epistemic intuitions of Western college students and East Asian college students.
In March 2006, Miami University Provost Jeffrey Herbst recommended to Miami University President Dr. James C. Garland that the Western College Program be phased out in favor of expanding Miami's Honors Program.