The Spillmans remained in Monmouth until 1894, the year after E.A. Bryan became the third president of the newly opened Washington Agricultural College and School of Science, now Washington State University, in Pullman.
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One of the Spillman sisters and her husband were living in nearby McMinnville.
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In 1902 he accepted a position with the U.S. Department of Agriculture following the reception of his paper on his wheat-breeding experiments presented at the meeting of the Association of American Agricultural Colleges and Experiment Stations in Washington, D.C. in November, 1901.
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In 1905 the Office of Farm Management was organized with Spillman as the head, a position he retained until 1918 when a disagreement with the Secretary of Agriculture elicited his resignation.
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