Rei appears in many spin-offs and other media related to Neon Genesis Evangelion including video games such as Evangelion 64 and the popular cross-over franchise Super Robot Wars and the various manga adaptations, such as Yoshiyuki Sadamoto's manga adaptation of the anime.
At the 2013 Tokyo Anime Fair, Gainax announced that they are finally producing the Blue Uru film with Honneamise veterans Hiroyuki Yamaga as the director and screenwriter and Yoshiyuki Sadamoto as the character designer, but without Hideaki Anno's involvement in the project.
Sadamoto also worked as an artist for the cover of Eric Clapton's album Pilgrim.