Zabelle C. Boyajian was born in Diarbekir (one of the ancient Armenian capitals, Tigranakert) into the family of the British Vice-Consul in Diarbekir and Harput Baron Thomas Boyajian and Catherine Rogers, a descendent of the English poet Samuel Rogers.
Armenian American Political Action Committee (A.A.P.A.C.), was founded by Albert A. Boyajian.