The battle of al-Musayfirah was one of the major military engagements between Druze rebels and the French Army on 17 September 1925, during the early stage of the Great Syrian Revolt, which continued on until 1927.
During the French Mandate period, Deir al-Bukht was the center of the 'Al al-Zubi clan which controlled a total of 16 villages in the Hauran, including Khirbet Ghazaleh and al-Musayfirah, and provided the local religious leadership of the Qadiriyya, Sufi Muslim order dating back to the 12th-century.