X-Nico

unusual facts about androgen


Androgen

Neural injections of Bromodeoxyuridine (BrdU) were applied to males of both groups to test for neurogenesis.


Androstenediol

4-Androstenediol, a steroid androgen which acts as a prodrug to testosterone

5-Androstenediol, a steroid androgen which is an endogenous precursor for testosterone

Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency

Because 11β-hydroxylase activity is not necessary in the production of sex steroids (androgens and estrogens), the hyperplastic adrenal cortex produces excessive amounts of DHEA, androstenedione, and especially testosterone.

Enzalutamide

When LNCaP cells (a prostate cancer cell line) engineered to express elevated levels of AR (as found in patients with advanced prostate cancer) were treated with enzalutamide, the expression of androgen dependent genes PSA and TMPRSS2 was down regulated in contrast to bicalutamide where the expression was upregulated.

MENT

Trestolone (7α-methyl-19-nortestosterone) a synthetic androgen developed for male contraception

Muscle atrophy

A novel class of drugs, called SARM (selective androgen receptor modulators) are being investigating with promising results.

Siblicide

Cattle Egrets, Bubulcus ibis, exhibit asynchronous hatching and androgen loading in the first two eggs of their normal three-egg clutch.

Stan Lazaridis

His time there was tainted when in January 2007, Lazaridis returned a positive drug test for anti-androgen Finasteride, a prescription alopecia medication, which was banned at the time.


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