Since October 2004, Dignitas has been working particularly in Zomba District, Malawi in partnership with the Malawi Ministry of Health, providing antiretroviral (ARV) therapy to thousands of children and adults in the country.
Since 1976 Erik De Clercq has collaborated on the development of new antiretroviral drugs with Antonín Holý, of the Institute of Organic Chemistry and Biochemistry (IOCB) of the Czechoslovak Academy of Sciences in Prague, Czech Republic.
In 1987 Corey directed the AIDS Clinical Trials Group, or ACTG, which conducted pivotal clinical trials confirming the use of the antiretroviral drug AZT to reduce maternal-fetal transmission of HIV and the usefulness of highly active antiretroviral therapy (HAART).
In 2005, according to Reuters, Rath's foundation distributed tens of thousands of pamphlets in poor black South African townships, such as Khayelitsha, claiming that HIV medication was "poison" and urging HIV-positive people instead to use vitamins such as those Rath sells to treat HIV/AIDS.