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He may be the Macarius, bishop of Magnesia, who, at the Synod of the Oak in 403, brought charges against Heraclides, bishop of Ephesus, the friend of John Chrysostom, although Adolf Harnack dated him in the late third century.
In 1644, he argued for the biblical validity of presbyterian church government, with his views being published as The angel of the Church of Ephesus no bishop of Ephesus, distinguished in order from, and superior in power to a presbyter, dedicated to William Twisse.