Joseph Thomas Clover invented an apparatus for the inhalation of chloroform in 1862 that consisted of a large reservoir bag lined with goldbeater's skin to make it airtight, into which a known volume of liquid chloroform was injected.
James Young Simpson (1811–1870), Scottish doctor and pioneer in use of chloroform as anaesthetic
The movie My Letter to George, or “Mesmerized”, with Jodie Foster was "... loosely based on that of Adelaide Bartlett, who, in 1886, went on trial for the chloroform poisoning of her husband.
In 2009, the Taiwanese Environmental Protection Administration Executive Yuan (EPA) found that the soil and the groundwater in the area close to Formosa Plastics' Renwu Plant has been polluted by benzene, chloroform, dichloromethane, 1,1,2-Trichloroethane, 1,1-dichloroethylene, tetrachloroethylene, trichloroethylene, and vinylchloride.
(This idea was presented in Anthony Trollope's 1882 novel The Fixed Period, which envisaged a College where men retired at 67 and after a contemplative period of a year were 'peacefully extinguished' by chloroform.
He is noted for being among the first physicians in North America to employ chloroform as a surgical anesthetic, a procedure he first performed on 5 February 1848, within 90 days of the first-ever application of chloroform as an anesthetic by James Young Simpson in Edinburgh.