Isotretinoin (13-cis-retinoic-acid; brand name Roaccutane), which is often used to treat severe acne, is such a strong teratogen that just a single dose taken by a pregnant woman may result in serious birth defects.
Jepson was born with a congenital jaw defect - her top jaw stuck out by eight millimetres and her lower jaw hung down into her neck.
When testing the effect of unc-5::intron::unc-5 transgene on a mislocalization defect in UNC-5 mutant animals at 25°C a significant rescue of the mislocalization defect was observed.
Major depressive disorder | bipolar disorder | obsessive-compulsive disorder | Disorder in the Court | Borderline personality disorder | Bipolar disorder | Substance use disorder | Dissociative identity disorder | Congenital disorder | Attention Deficit Hyperactivity Disorder | Vision of Disorder | Social anxiety disorder | Posttraumatic stress disorder | Narcissistic personality disorder | antisocial personality disorder | pervasive developmental disorder | Obsessive–compulsive disorder | major depressive disorder | Esophageal motility disorder | eating disorder | dissociative identity disorder | conversion disorder | Congenital adrenal hyperplasia | Attention deficit hyperactivity disorder | X-linked congenital stationary night blindness | Vision of Disorder's | Speech disorder | Somatization disorder | social anxiety disorder | Sleep disorder |
Female health workers are exposed to hazardous drugs and chemicals in the workplace which may cause adverse reproductive outcomes such as spontaneous abortion and congenital malformations.
In 2009, Greenaction alleged that there was a cluster of birth defects in Kettleman City, after five infants were born with cleft lip and/or palate between September 2007 and November 2008.
In February 2005, three infants were born with birth defects to migrant farmworkers within eight weeks of each other in Collier County, Florida.