AP endonuclease, specifically, catalyze the incision of DNA exclusively at AP sites, and therefore prepare DNA for subsequent excision, repair synthesis and DNA ligation.
Flap structure-specific endonuclease 1 | endonuclease | DpnII restriction endonuclease family | AP endonuclease |
The components of the system are MutS, which binds to the GT mismatch, the VSR endonuclease, which cuts the DNA, and MutL, which recruits the UvrD helicase.