Jonas Frisén and his colleagues at the Karolinska Institute in Stockholm provided evidence that ependymal cells act as reservoir cells in the forebrain, which can be activated after stroke and as in vivo and in vitro stem cells in the spinal cord.
In the holocephalan species Chimaera monstrosa (ratfish), he described, in the basal midline of the diencephalon, a previously unknown ependymal structure adjacent to the rostral part of the optic chiasma referred to as the ‘organon vasculare praeopticum’.