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Threats to the species include its low numbers and limited gene pool, degradation of its habitat by axis deer, and feral pigs, damage to plants by slugs, rats, and birds, and competition by exotic plants such as climbing dayflower (Commelina diffusa), air plant (Kalanchoe pinnata), and castor bean (Ricinus communis).
Various captive breeding programmes are in place — notably at the Giraffe Centre in Nairobi, Kenya — which aim to expand the gene pool in the wild population of Rothschild's giraffe.
This outcome not only benefits large mammal migration, but yields an improved gene pool.
In addition to the Ainu, other present-day hunter-gatherer societies that have remained isolated in northeast Asia and North America and whose ancestors may have contributed to the gene pool of Paleoindian are the Yukaghir, Inuit, Aleut, Koniag, Kamchadal, Chukchi, and Koryak.