Mannitol 5% has a diuretic effect and can also cause hypotension and circulatory collapse.
Metaraminol or ephedrine, where hypotension (low blood pressure) may occur secondary to the sedating drugs
Capillary leak syndrome a rare medical condition where the number and size of the pores in the capillaries are increased which leads to a leakage of fluid from the blood to the interstitial fluid, resulting in dangerously low blood pressure hypotension, edema and multiple organ failiure due to limited perfusion