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His protest consequently resulted in legal battles with the Shell Oil Company (US), and ultimately his death, at the age of 65, due to the liver failure that apparently resulted from his 4 month liquid fast following his loss in the courtroom and subsequent loss of his business, and his home.
Datuk K. Pathmanaban died due to kidney and liver failure at the Pantai Medical Centre in Kuala Lumpur at around 1am on June 9, 2001.
This may be a clinical sign of hypoalbuminaemia (low albumin), which can be seen in nephrotic syndrome (a form of kidney failure), liver failure, protein malabsorption and protein-losing enteropathies.
In Singapore, a high-profile liver failure of female television personality Andrea De Cruz sent shockwaves across its local television industry, leading to a few lawsuits being filed.
Modifying mate in this fashion is potentially toxic, as these alkaloids can cause a rare condition of the liver, veno-occlusive disease, which produces liver failure due to progressive occlusion of the small venous channels in the liver.