Edith goes through menopause in the second season ("Edith's Problem"), discovers a lump in her breast just before Christmas in the fourth season ("Edith's Christmas Story"), is nearly raped on her 50th birthday in the eighth season ("Edith's 50th Birthday"), and develops phlebitis in the show's final episode in season nine ("Too Good Edith").
Hot flashes, a common symptom of menopause and perimenopause, are typically experienced as a feeling of intense heat with sweating and rapid heartbeat, and may typically last from two to thirty minutes for each occurrence, ending just as rapidly as they began.