Most monoclonal antibodies have been purified using affinity chromatography based on immunoglobulin-specific Protein A or Protein G, derived form bacteria.
Immunosuppressive drugs such as the therapeutic monoclonal antibody Daclizumab, Cyclosporine and Methotrexate have proven to be effective treatment options for birdshot chorioretinopathy.
Treatment modalities include antiviral drugs such as ganciclovir for human herpesvirus type 8 (HHV-8), chemotherapy, corticosteroids, immunomodulators, monoclonal antibodies against IL-6, and thalidomide.
By the late-1970s, however, three new revolutionary techniques had been developed: recombinant DNA, monoclonal antibodies, and gene expression, the foundations of the biotechnology industry.
He further generated monoclonal antibodies specific for the hematopoietic stem cell marker, CD34.
The advantages of using monoclonal antibodies compared to using polyclonal antibodies includes: High homogeneity, absence of nonspecific antibodies and no batch-to-batch or lot-to-lot variability.
Bi-specific T-cell engager, or BiTE, a class of bispecific monoclonal antibodies