ULK1 and ULK2 (unc-51-like kinase) have been reported to have an additional function in neuronal development, e.g. outgrowth regulation of mouse neurons.
In June 1987, a Phase I clinical trial was launched at Weill Medical College of Cornell University to study a gene therapy method for treatment of the signs and symptoms of late infantile neuronal ceroid lipofuscinosis (LINCL).
Experiments in a rat neuronal cell culture model suggested that this gene may be regulated directly or indirectly by MEF2 site binding proteins.
They were first reported by Santiago Ramón y Cajal in 1903, who called them nucleolar accessory bodies due to their association with the nucleoli in neuronal cells.
Mutations in this gene, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease, also known as Juvenile Neuronal Ceroid Lipofuscinosis (JNCL) or Juvenile Batten disease.
Mutant atrophin-1 proteins have been found in neuronal intranuclear inclusions (NII) and diffusely accumulated in the neuronal nuclei.
Research areas include: Molecular genetics of blinding eye diseases and brain disorders; Treatment, biophysics and psychophysics of glaucoma; Eye movement and control mechanisms; Neuronal damage; Retinal degeneration and diabetic retinopathy; Corneal disease
In collaboration with his postdoctoral fellow, Antony "Tony" Stretton, Ed began developing a technique to visualize the structure of neurons in order to determine whether neuronal shapes are genetically specified.
Some applications of the FGMOS are digital storage element in EPROM, EEPROM and flash memories, neuronal computational element in neural networks, analog storage element, digital potentiometers and single-transistor DACs.
His research focuses on the organization and evolution of neuronal circuits in teleost fishes, the evolution of neuronal circuits for bird song learning in parrots and songbirds and how evolution modifies the processes of brain development to generate a broad diversity of adult brains.
Latexin, a protein possessing inhibitory activity against rat carboxypeptidase A1 (CPA1) and CPA2 (MEROPS peptidase family M14A), is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat.
The 1981 book Genes, Mind, and Culture: The Coevolutionary Process by Charles J. Lumsden and E. O. Wilson proposed the theory that genes and culture co-evolve, and that the fundamental biological units of culture must correspond to neuronal networks that function as nodes of semantic memory.
Makeyev et al. showed that miR-124 directly targets PTBP1 (PTB/hnRNP I) mRNA, which encodes a global repressor of alternative pre-mRNA splicing in non-neuronal cells.
NeuN, a protein marker of neurons, concentrated in neuronal nuclei
Through interaction with the ErbB family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells.
PLEKHM3 is thought to interact with a protein called GDAP1, which is responsible for differentiation in neuronal cell types and plays a role in the signal transduction pathway.
Depolarization and hyperpolarization of neuronal membrane potentials (in neuroscience).
Hobson and McCarley hypothesized that a brain stem neuronal mechanism sends pontine-geniculo-occipital (or PGO) waves that automatically activate the mammalian forebrain.
Dehaene has developed computational models of consciousness, based on Bernard Baars Global Workspace Theory, which suggest that only one piece of information can gain access to a "global neuronal workspace".
Barry had initially found it difficult to believe in her acquisition of stereo vision for the reason that the notion of critical period was firmly set since the groundbreaking work of Torsten Wiesel and David H. Hubel with deprivation experiments in which animals did not develop the neuronal basis for stereo vision if they were prevented from performing stereo fusion for a given time period after birth.
In 1977, at the same laboratory at Yale University, this first neuronal phosphoprotein was purified and initially characterized by Tetsufumi Ueda and Nobel Prize winner Paul Greengard.
To understand the future of synaptic noise research, it would be essential to discuss the work of Alain Destexhe, a Belgian doctor who has greatly studied the importance of synaptic noise in neuronal connections.