The RNA is always found within an operon encoding subunits of ATP synthase, and it is always located downstream of the gene encoding the A subunit of ATP synthase, and upstream of the C subunit gene.
The gab operon is responsible for the conversion of γ-aminobutyrate (GABA) to succinate.
These experiments confirmed the mechanism of the lac operon, earlier proposed by Jacques Monod and Francois Jacob.
Along with examination of conserved synteny, conserved operon structure, or "Rosetta Stone" domain fusions, comparing phylogenetic profiles is a designated a "post-homology" technique, in that the computation essential to method begins after it is determined which proteins are homologous to which.
The name RTX (repeats in toxin) refers to the glycine and aspartate-rich repeats located at the C-terminus of the toxin proteins, which facilitate export by a dedicated T1SS encoded within the rtx operon.
Discovered in 1953 by Jacques Monod and colleagues, the trp operon in E. coli was the first repressible operon to be discovered.
The terminator structure is recognised as a termination signal for RNA polymerase and the operon is not transcribed.