miR-451 regulates the drug-transporter protein P-glycoprotein, potentially promoting resistance to the chemotherapy drug Paclitaxel.
Paclitaxel | paclitaxel |
Monroe Eliot Wall (1916 – July 6, 2002) was an American chemist, who co-discovered, with Mansukh C. Wani, paclitaxel and camptothecin, two anti-cancer drugs considered standard in the treatment to fight ovarian, breast, lung and colon cancers.