Salicylic acid plays a role in the resistance to pathogens by inducing the production of pathogenesis-related proteins.
1) the role of mating and switching in the pathogenesis of Candida albicans,
He developed the use of twin studies in the assessment of the relative roles of heredity and the environment in the pathogenesis of psychiatric disease.
Studies of the pathogenesis and risk factors of KBD have proposed selenium deficiency, inorganic (manganese, phosphate...) and organic matter (humic acids and fulvic acids) in drinking water, fungi on self-produced storage grain (Alternaria sp., Fusarium sp.), producing trichotecene (T2) mycotoxins.
The pathogenesis of this condition appears to be due to over expression of two genes - GDF6 and SDC2.
The gene ring finger protein 213 (RNF213) has been implicated in the pathogenesis of this disease.
"These mechanisms present us with novel targets that might form the basis for the development of an entirely new class of antimicrobials," said Professor Dr. Jorge Galan, senior author of the paper and the Lucille P. Markey Professor of Microbial Pathogenesis and chair of the Section of Microbial Pathogenesis at Yale.
None of the in vivo or in vitro studies performed with toxic-oil-specific components, such as fatty acid anilides and esters of PAP, have provided evidence that these markers are causally involved in the pathogenesis of TOS.