The building was founded in 1307 as a college for a dean and twelve secular priests by Sir Robert de Holland, who was secretary to Thomas Plantagenet, Earl of Lancaster.
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Born in La Boissière, Calvados, Lambert de la Motte was recruited by Alexander de Rhodes as a secular clergy volunteer to become a missionary in Asia, together with François Pallu and Ignace Cotolendi.
Sebastián Montero (born in Écija) was a Spanish secular priest who was active in the later half of the sixteenth century in North America.
His chief topics are the iniquities of the friars, and the defence of the secular clergy of the University of Paris against their encroachments; and he delivered a series of eloquent and insistent poems (1262, 1263, 1268, 1274) exhorting princes and people to take part in the Crusades.