The Court rejected a challenge by the generic drug manufacturers Novopharm and Apotex to declare Glaxo Wellcome's patent for AZT, an AIDS-fighting drug, invalid.
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In February 1985, the NIH reported the positive results of their screening to Glaxo Wellcome, and, on March 16, 1985, Glaxo Wellcome filed a patent application for a new use of AZT in the United Kingdom.
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One of the drugs screened at that time is what is now known as AZT.
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In vitro testing on mouse cells revealed that AZT was potentially effective against AIDS.
In 1987 Corey directed the AIDS Clinical Trials Group, or ACTG, which conducted pivotal clinical trials confirming the use of the antiretroviral drug AZT to reduce maternal-fetal transmission of HIV and the usefulness of highly active antiretroviral therapy (HAART).
Zidovudine | zidovudine |
Anemia of chronic disease as it is now understood is to at least some degree separate from the anemia seen in renal failure in which anemia results from poor production of erythropoietin, or the anemia caused by some drugs (like AZT, used to treat HIV infection) that have the side effect of inhibiting erythropoiesis.