Scenes of the 1965 episode "Ed the Pilot" of the television show Mister Ed were shot at Van Nuys Airport in front of the hangar of the 146th Air Transportation Wing.
The training is coordinated with the Air Force Reserve's 302d Airlift Wing at Colorado's Peterson Air Force Base, the Air National Guard's 153d Airlift Wing from Cheyenne, Wyoming, the 146th Airlift Wing from Port Hueneme, California, and the 145th Airlift Wing from Charlotte, North Carolina.
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In December 1988, after more than six decades of California Air National Guard flying tradition in the San Fernando Valley, the 146th Airlift Wing began moving from Van Nuys Air National Guard Base to a brand new facility, built on Federal land leased to the State of California, adjacent to the Naval Air Warfare Center Weapons Division and NAS Point Mugu, an active duty Navy flying installation.