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The only report of it in the chemical literature was a paper published by Marc Julia's group at the Pasteur Institute in 1965.
It is metabolized by the enzyme 7α-hydroxycholest-4-en-3-one 12α-hydroxylase to 7α,12α-dihydroxycholest-4-en-3-one and then to cholic acid, the major primary bile acid in humans.
It is a member of the class of compounds known as anthocyanidins and is a hydroxy derivative of pelargonidin.
The latter is a leucine metabolite produced in the body through oxidation of the ketoacid of leucine (ketoisocaproate, KIC).
Root bark of D. illinoensis has been found to contain N,N-DMT, NMT, N-hydroxy-N-methyltryptamine, 2-hydroxy-N-methyltryptamine, and gramine (toxic).
Dihydrochalcones (3′,5′-dihydroxy-2′,4′,6′-trimethoxydihydrochalcone, methyl linderone, 5-hydroxy-6,7,8-trimethoxyflavone (alnetin) and 2′-hydroxy-3′,4′,5′,6′-tetramethoxydihydrochalcone (dihydrokanakugiol) can be found in twigs of Lindera lucida.
The Fries rearrangement, named for the German chemist Karl Theophil Fries, is a rearrangement reaction of a phenyl ester to a hydroxy aryl ketone by catalysis of Lewis acids.
Lignans, such as 6“ - bromo - isoarboreol, 4-hydroxysesamin, 4,8-dihydroxysesamin, 1,4-dihydroxysesamin (gummadiol), 2-piperonyl-3-hydroxymethyl-4-(α-hydroxy-3,4-methylenedioxybenzyl)-4-hydroxytetrahydrofuran and the 4-O-glucoside of 4-epigummadiol, can be isolated from the heartwood of Gmelina arborea.
Hydroxyquinol 1,2-dioxygenase is an enzyme that uses hydroxyquinol and O2 to produce 3-hydroxy-cis,cis-muconate.
Barton–McCombie deoxygenation, organic reaction replacing a hydroxy group with hydrogen to give an alkyl group
Early 1950s – Monsanto begins metabolism studies and the development of methionine hydroxy analogue (MHA feed supplement) production begins at Monsanto's Everett, Massachusetts location.
The Nucleoside analogs, d4T, 3'-fluoro-3'-deoxythymidine (FLT) and 3'-fluorodideoxyguanosine (FLG), and the NNRTI's 1-(2-hydroxy-ethoxy) methyl-6-phenylthiothymine (HEPT), tetrahydro-imidazo4,5,1-jk1,4-benzodiazepine-2(1H)-one and -thione (TIBO) and alpha-anilinophenylacetamide (alpha-APA) were first described at the Rega Institute.
Tryptophan and 5-hydroxy-tryptophan, for instance, can be used to help the body replenish serotonin levels in the brain after the use of MDMA, and vitamin supplements are appropriate for users of stimulants such as amphetamine.