Next, they suggested that k-Ras becomes activated and the polyp becomes a small, benign adenoma.
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Volgelstein et al. went on to suggest that loss of the DCC gene and of p53 result in a malignant adenocarcinoma.
The DNA-Doxorubicin complex was taken up by human breast adenocarcinoma cancer cells (MCF-7) via cellular internalization with much higher efficiency than doxorubicin in free form.
Interleukin 10 knock out mice develop invasive adenocarcinoma in the colon.