He served as apostolic administrator of Pamplona, Spain from 1520 to 1538; that of Alessano, Italy from 1526 to 1531; that of Otranto, Italy from 1526 to 1536; that of Gerace, Italy from 1536 to 1538; that of Catanzaro, Italy briefly in 1536; that of Oppido Mamertina, Italy from 1536 to 1538 (resigning in favor of his natural son, Ascanio Cesarini, who succeeded him in that see from 1538 to 1542); and that of Cuenca, Spain from 1538 to his death.