Cyclophosphamide, an alkylating agent which damages DNA by binding to it and causing the formation of cross-links
free agent | Agent Orange | agent | Talent agent | double agent | literary agent | Political Agent | Free agent | Paranoia Agent | Agent Cody Banks | The Secret Agent | Secret Agent X-9 | MRI contrast agent | Fear Agent | Agent Provocateur | Thickening agent | The Station Agent | station agent | Moscow hostage crisis chemical agent | John Johnston (Indian Agent) | Invisible Agent | General Agent | Forté Agent | Election agent | Confidential Agent | Chemical Agent Resistant Coating | Bacteriostatic agent | Alkylating antineoplastic agent | Agent to the Stars | Agent Provocateur (lingerie) |
For example, cancer patients can be more sensitive to treatment with DNA alkylating agents if the promoter of the DNA repair gene MGMT of the patient is methylated.
Mannomustine (INN), also known as mannitol nitrogen mustard, tradename Degranol is an old alkylating antineoplastic agent from the group of nitrogen mustards.