Michael J. Fox, Nathan Lane, Steve Zahn, Geena Davis, Jonathan Lipnicki, and others do not reprise their roles as Stuart, Snowbell, Monty, Eleanor Little, and other characters from the movies and are replaced by David Kaufman, Kevin Schon (in some episodes by Quinton Flynn), André Sogliuzzo, Jennifer Hale, and Myles Jeffrey.
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Monty (voiced by André Sogliuzzo) is Snowbell's old friend who still wants to eat Stuart, though he does help him with his missions at times.
André Previn | André Breton | Andre Agassi | André Malraux | André Derain | Victor André Cornil | Carl Andre | Andre Ward | Fabrizio De André | André the Giant | André Heller | André Gide | André-Gaston Prételat | André | Andre Norton | André Masséna | André Guignard | André Franquin | Andre Begemann | Peter Andre | Andre Williams | Andre Ware | André Leon Talley | André Le Nôtre | André Glucksmann | André Charlot | André Sogliuzzo | André Marie Constant Duméril | André-Jacques Garnerin | André Bauer |
The game begins in the film's final scene, with the mansion of Tony Montana (voiced by André Sogliuzzo) being raided by assassins sent by Alejandro Sosa (Robert Davi).