The city was identified with the ancient Antikyra in 1806 by William Martin Leake, who found the first among the several known inscriptions mentioning its name.
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name Antikyra; until the early 20th century it was called "Aspra Spitia", a name given after 1960 to a wholly new adjacent settlement, 3 km to the East; in Phocis, on the bay of Anticyra, in the Corinthian gulf; some remains are still visible.
Desfina is built amphitheatrically and is located about 200 kilometres of Athens, roughly 35 kilometres of Livadia, 16 kilometres of Antikyra, 30 kilometres of Amfissa, 18 kilometres of Itea and roughly 30 kilometres of Delphi and Arachova.
In antiquity, an effective emetic based on white hellebore and a bitter oval seed (which Hahneman believed was the seed of Erigeron or Senecio) was mixed by the physicians of Antikyra, a city of Phokis in Greece.