Apigenin, apigenin 7-O-glucoside, and a new acylflavone glucoside named echitin (I) were isolated from Echinops echinatus flowers.
Apigenin, a plant-derived flavanoid that has significant promise as a skin cancer chemopreventive agent, has been found to regulate normal human keratinocyte differentiation by suppressing involucrin, and this is associated with reduced cell proliferation without apoptosis.
Apigenin |