Testosterone (3 mg kg−1, s.c.) was administered to the rats along with the test extracts (50 and 100 mg kg−1, p.o.) for a period of 28 days.
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Apigenin, apigenin 7-O-glucoside, and a new acylflavone glucoside named echitin (I) were isolated from Echinops echinatus flowers.