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Alliquippa, her son Kanuksusy, and warriors from her band of Mingo Seneca traveled to Fort Necessity to assist George Washington but did not take an active part in the Battle of the Great Meadows on July 3–4, 1754.
In order to ensure the compliance of the surrender terms agreed to by Major George Washington following the Battle of the Great Meadows, he and Captain Jacob Van Braam were left as prisoners-of-war on July 28, 1754 in the care of Captain Coulon de Villiers at Fort Duquesne until at such time they could be released in a prisoner exchange.
After the British defeat at the Battle of the Great Meadows and the evacuation of Fort Necessity, Alliquippa moved her band to the Aughwick Valley of Huntingdon County, Pennsylvania for safety.