Founded by Ricky Cool and Andy Silvester in 1984 and known as Ricky Cool and the Big Town Playboys, they covered American music from the 1940s and 1950s, such as that of Amos Milburn and Little Walter.
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In May 2005, the band teamed up with Gary Brooker and Andy Fairweather Low to give a charity concert called "Aftershock" in India, with all proceeds to benefit victims of the tsunami caused by the 2004 Indian Ocean earthquake.
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Sanchez and the Big Town Playboys headlined many European music festivals and worked with several noted blues musicians, such as Jimmy Nelson, Lowell Fulson, Carey Bell, Don and Dewey, Little Willie Littlefield and Joe Hughes.